Targeting cellular structures producing DON to reduce mycotoxin in the grain. The enzymes for DON biosynthesis are localized to the structures in red, that we call “toxisomes”, which are highly modified portions of the endoplasmic reticulum. Toxisomes are found close to the nucleus of the cell (in green) or stand-alone apart from the nucleus. Left are the structures shown by transmission electron microscopy, and on the right, by fluorescent confocal microscopy with 3-D reconstruction. Publication: Boenisch, M.J., Broz, K.L., Purvine, S.O., Chrisler, W.B., Nicora, C.D., Connolly, L.R., Freitag, M., Baker, S.E., Kistler, H.C. 2017. Read more about Targeting cellular structures producing DON to reduce mycotoxin in the grain.