Prosaro Pro®, a premix of the demethylation inhibitor (DMI) fungicide active ingredients (AI) tebuconazole and prothioconazole and the succinate dehydrogenase (SDHI) AI Fluopyram, and Sphaerex®, a premix of the DMIs metconazole and prothioconazole, are new fungicides marketed as possible replacements for industry standards such as Prosaro and Caramba for Fusarium head blight (FHB) and deoxynivalenol (DON) control. In addition, Miravis Era®, a new premix of Pydiflumetofen, a relatively new member of the SDHI family of compounds, and the DMI prothioconazole, is being tested for efficacy against FHB and DON. In 2024, uniform fungicide trials were conducted in 24 US states to compare existing and new fungicides for FHB and DON management in single- and double-application treatment programs, consisting of: Prosaro (I), Caramba (II), Miravis Ace (III), Prosaro Pro (IV), or Sphaerex (V) applied at anthesis, Miravis Ace at anthesis followed by an application of Prosaro Pro (VI), Sphaerex (VII), or Tebuconazole (VIII) at 4-6 days after anthesis, Miravis Era at anthesis, plus a non-treated check (CK). FHB index (IND) was assessed, and grain samples were collected and assayed for DON. Across environments, mean IND and DON in the checks ranged from 0 to 47% and 0 to 9.4 ppm, respectively. All fungicide treatments resulted in significantly (P < 0.001) lower mean IND and DON than CK. Although differences among fungicide programs were not always significantly significant for IND, treatment VII, VII and Miravis Era resulted in the lowest mean IND values. Treatment VII had significantly (P < 0.001) lower mean DON than treatments I and III. Miravis Era was not significantly different from treatment I, II, III, IV and VII for FHB index (P > 0.122). However, mean DON were significantly lower for V, VI, and VII than Miravis Era. Based on these results, all treatments were of similar efficacy against IND, but the double-application treatments VI and VII were the most effective against DON contamination of grain.
ACKNOWLEDGEMENTS AND DISCLAIMER: This material is based upon work supported by the U.S. Department of Agriculture, under Agreement Nos. 59-0206-8-195, 59-0206-0-126; 59-0206-9-120, 59-0206-0-125; 59-0206-6-008, 59-0206-0-153; 59-0206-5-007, 58-6070-9-019, 59-0206-0-184; 59-0206-8-192, 59-0206-0-115; 59-0206-8-189, 59-0206-0-138; 59-0206-5-005, 59-0206-9-122, 59-0206-0-139; 59-0206-8-190, 59-0206-0-141; 59-0206-6-015, 59-0206-0-155; 59-0206-4-016, 59-0206-9-117, 59-0206-0-132; 59-0206-8-210, 59-0206-0-140; 59-0206-8-199, 59-0206-0-122; 59-0206-8-211, 59-0206-0-144; 59-0206-0-173; 59-0206-0-188; 58-2050-8-013, 59-0206-0-175; 59-0206-6-010; 59-0206-8-189; 59-0206-0-179; 59-0206-6-012, 59-0206-0-189; 59-0206-9-123, 59-0206-0-118; 59-0206-6-014, 59-0206-0-191; 59-0206-9-009, 59-0206-0-185; and 59-0206-8-187, 59-0206-0-131. This is a cooperative project with the U.S. Wheat & Barley Scab Initiative. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the view of the U.S. Department of Agriculture.