Canada Western Red Spring (CWRS) wheat is highly desired globally for a wide variety of end-use in the wheat industry. Canada ranks fifth in the world for hard red spring wheat production, vast majority of which is produced in western Canada. Canada produces approximately 30 million metric tonnes of wheat, of which 20 million metric tonnes (67%) is exported, contributing about $8 billion dollars to the Canadian economy annually. Majority of the spring wheat is grown in the prairie provinces where disease infestation is widespread. Fusarium head blight (FHB), caused by Fusarium graminearum, is one of the most devastating diseases of wheat causing major yield losses, grade reduction, and grain toxicity. Currently, losses to the wheat industry in Canada due to FHB is up to $300 millions annually. Severe outbreaks happen frequently in the Canadian Prairies necessitating the need for management of FHB disease. Cultivation of wheat varieties with sub-optimum levels of resistance, which also act as an overwintering source of inoculum, is considered one of the main reasons of FHB disease outbreaks. Currently, a spring wheat AAC Tenacious and a winter wheat Emerson, are the only two varieties rated resistant to FHB. Majority of the cultivars currently grown are rated moderately-resistant or intermediate resistant. Breeding programs are currently accessing germplasm in the CWRS class with better agronomics, end use quality and high levels of FHB resistance. The presentation will discuss the development of farm-ready FHB tolerant wheat varieties using maker assisted selection and field phenotyping, which will mitigate disease outbreaks, and reduce economic losses. The new varieties are incorporated into the breeding programs as crossing parents to pyramid additional sources of FHB resistance for sustainable management of the disease.